Transportation

Major highways

• Highway 401 (the Macdonald-Cartier Freeway, connecting Windsor-Detroit to Quebec),
• Highway 403 (to Hamilton via the QEW in Oakville/Burlington),
• Highway 407 (toll route across the north end of the city),
• Highway 409 (providing access directly into Pearson Airport terminals from Toronto),
• Highway 410 (to Brampton),
• Queen Elizabeth Way (to Niagara Falls and Buffalo), and
• Highway 427, straddling the Toronto-Mississauga Boundary, with access into Toronto Pearson International Airport.

Rail

Mississauga is on three major railway lines (two owned by Canadian National Railway and one owned by Canadian Pacific Railway), which lead into and around Toronto. The GO Transit commuter rail service provides service into Toronto's Union Station along the Lakeshore West (GO Transit), Georgetown (GO Transit), and Milton (GO Transit) lines. VIA Rail service in the Quebec City-Windsor Corridor is provided on both CN lines, although there are no stops in Mississauga.

Bus

• The Greater Toronto Area's GO Transit service also provides an extensive intercity bus service, which connects Mississauga to downtown Toronto and neighbouring suburban hubs including academic institutions as McMaster University (in Hamilton), Sheridan College in Oakville, York University, Seneca College, Centennial College, University of Toronto at Scarborough all within Toronto, and Durham College and the University of Ontario Institute of Technology in Oshawa, Ontario.
• The city's Mississauga Transit service provides relatively frequent bus service across the city, and connects to the Toronto Transit Commission's subway and GO Transit (a busway similar to Ottawa's Transitway is being built). There are also connections to Oakville Transit, and Brampton Transit, with routes going beyond these borders. There are also plans for the construction of an LRT (similar to Calgary) along Hurontario Street ("Highway 10," the city's main street), and possibly on some other busy streets.

Air

Toronto Pearson International Airport (YYZ) in northeastern Mississauga (Malton) is a hub for Air Canada and provides flights to all regional, national, and international destinations.